With the arrival of the Golden Legion in Nexal, Hoxitl conspired with the Ancient Ones in order to have Naltecona put to death and the Viperhands cult take control of the empire. Hoxitl continued to hunt for Erixitl, also obtaining the reluctant help of Shatil, brother of Erixitl and a priest of Zaltec.
Despite his transformation, Hoxitl remained a servant of Zaltec, albeit a reluctant one, and unleashed the Viperhands monsters upon the human survivors. In time, the transformation started to afflict his mind as well and Hoxitl became more and more bestial. He led the Viperhands armies in the Second Battle of Ulatos until, with the banishment of the avatar of Zaltec, all the monsters lost their will for battle and retreated to Nexal.
As of 1362 DR, Hoxitl still ruled the ruins of Nexal.