Needle could refer to:
- The green dragon Ormalagos, also known as "Needle."
- Needle, a treant.
- Needle's Bones, a sinkhole in Chult, and final resting place of Ormalagos.
- The Needle, a water tower in Luskan.
- Needle Leap, a chasm in the East Rift.
- Needle Peak, a mountain in the Ice Spires.
- Stoner's Needle, a mountain on the Sword Coast.
- Kozah's Needle, a magical staff used by Dahlia Sin'felle.
- The Needle of the Crossroads, a magical artifact that could create portals.
- Locust needle, a type of tree found on the Pirate Isles.
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